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    Tamoxifen is the main hormone treatment used for breast cancer in women who haven't yet gone through the menopause. It's sometimes also used to treat post-menopausal women. Tamoxifen can be used in several different ways for breast cancer, depending on the stage of the cancer and what other treatment options are used. Most women take tamoxifen for five years after having surgery, chemotherapy or radiotherapy (or a combination of these) for their breast cancer. The tamoxifen reduces the risk of the cancer coming back and also reduces the risk of getting cancer in the other breast. Some women may take tamoxifen for two or three years and then switch to a different hormonal therapy. Sometimes tamoxifen can be used to help shrink a large tumour before having surgery; for some women this can help avoid having a mastectomy. buy tetracycline online usa Antineoplastic action: Exact mechanism of action is unclear. Tamoxifen may exert its cytotoxic action by blocking estrogen receptors within tumor cells that require estrogen to thrive. The estrogen receptor-tamoxifen complex may be translocated into the nucleus of the tumor cell, where it inhibits DNA synthesis. Contraindicated in pregnant women and in patients hypersensitive to drug. Also contraindicated for risk reduction in high-risk women who also take coumarin-type anticoagulants or who have a history of deep vein thrombosis or pulmonary edema. have an increased risk of acute neurotoxicity (tremor, hyperreflexia, unsteady gait, and dizziness). Symptoms may arise within 3 to 5 days of starting therapy; they’re expected to clear 2 to 5 days after stopping therapy. Discuss the potential benefits versus the potential risks with women considering treatment to reduce their risk of developing breast cancer. Benefits of therapy outweigh risks in women diagnosed with breast cancer.

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    Oct 19, 2017. Information about taking tamoxifen for breast cancer or infertility treatment, including how does tamoxifen work, tamoxifen side effects. doxycycline bacterial coverage Oct 16, 2018. Tamoxifen is the oldest of the hormonal therapies, drugs that block the effects of estrogen in the breast tissue. Tamoxifen is approved by the. Tamoxifen prescription and dosage sizes information for physicians and healthcare professionals. Pharmacology. Tamoxifen as citrate 10mg, 20mg; tabs.

    Tamoxifen belongs to the group of cancer-fighting medications known as antineoplastics, and specifically to the type of antineoplastics known as antiestrogens. It is used in combination with other medications to treat early breast cancer. Tamoxifen fights certain types of breast cancer, called hormone responsive or estrogen receptor positive breast cancer, by blocking the effects of the hormone estrogen in the body. This prevents the growth of the types of breast cancer cells that require estrogen for growth and survival. It is also used to treat breast cancer that is advanced or has spread to other parts of the body. This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. Tamoxifen blocks the actions of estrogen, a female hormone. Certain types of breast cancer require estrogen to grow. Tamoxifen is used to treat some types of breast cancer in men and women. It is also used to lower a woman's chance of developing breast cancer if she has a high risk (such as a family history of breast cancer). Use a barrier form of birth control (such as a condom or diaphragm with spermicide) while you are using this medication and for at least 2 months after your treatment ends. Tamoxifen may also be used for purposes not listed in this medication guide. You should not use tamoxifen if you are allergic to it, or if you have a history of blood clots in your veins or your lungs, or if you are also taking a blood thinner such as warfarin (Coumadin). Before using this medicine, tell your doctor if you have liver disease, high triglycerides (a type of fat in the blood), a history of cataract, or a history of stroke or blood clot. Also tell your doctor if you if you are receiving chemotherapy or radiation treatment.

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