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    To help you get a better understanding of some commonly prescribed medications-including their possible side effects, directions on how to take them, and potential drug interactions-we've compiled the following searchable list of drug information. IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs. CODEINE/PROMETHAZINE SYRUP- ORAL (proe-METH-a-zeen/KOE-deen) COMMON BRAND NAME(S): Phenergan w/ codeine WARNING : Taking codeine/promethazine with other medications that may also cause drowsiness or breathing problems may increase your risk of very serious side effects, including death. To lower your risk, your doctor should have you take the smallest dose of codeine/promethazine that works, and take it for the shortest possible time. Get medical help right away if any of these very serious side effects occur: slow/shallow breathing, unusual lightheadedness, severe drowsiness/dizziness, difficulty waking up. zoloft onset Promethazine was developed in the mid-1940s when a team of scientists from the French chemical manufacturing company Rhône-Poulenc combined phenothiazine and a diamine side chain of diphenhydramine to create a new drug. Their creation, promethazine, is a synthetic medication that belongs to a pharmaceutical family known as phenothiazines. As a medication, promethazine has several uses, including treating allergies, motion sickness, and more. It is also a strong sedative that is sometimes prescribed during labor, before and after surgery, and at other times. Promethazine is a first generation antihistamine that is only available by prescription. It effectively treats several conditions, such as: As an antihistamine, promethazine competes with histamine for binding at some of its receptor sites (H1-receptors), thereby blocking histamine from binding to many. This, in turn, prevents or reduces the typical effects of histamine activating those receptors, including hives, constriction of the airways, nausea, increased wakefulness, nasal congestion, sneezing, and a runny nose.

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    Taking codeine/promethazine with other medications that may also cause drowsiness or breathing problems may increase your risk of very serious side effects, including death. To lower your risk, your doctor should have you take the smallest dose of codeine/promethazine that works, and take it for the shortest possible time. Get medical help right away if any of these very serious side effects occur: slow/shallow breathing, unusual lightheadedness, severe drowsiness/dizziness, difficulty waking up. Show More This combination medication is used to treat symptoms caused by the common cold, flu, allergies, or other breathing illnesses (e.g., sinusitis, bronchitis). Promethazine is an antihistamine that relieves watery eyes, itchy eyes/nose/throat, runny nose, and sneezing. Codeine is an opioid cough suppressant (antitussive) that affects a certain part of the brain, reducing the urge to cough. Do not use this product in children younger than 18 years. There is a risk of serious (rarely fatal) side effects, such as breathing problems. Cough due to a common cold often does not need to be treated with medicine. Ask your doctor or pharmacist about other ways to relieve cough and cold symptoms, such as drinking enough fluids, using a humidifier, or saline nose drops/spray. Product Description: Promethazine Hydrochloride and Codeine Phosphate Syrup CV Description: 6.25 mg/10 mg per 5 m L Boysenberry Flavored Syrup Compare To: Phenergan® with Codeine Size: 473 m L Unit of Sale: 1 Type: Rx Orange Book: AA Storage: Store at 20° to 25°C (68° to 77°F) [see USP Controlled Room Temperature]. EACH 5 ML CONTAINS: Active: Promethazine Hydrochloride 6.25 mg, Codeine Phosphate 10 mg, Alcohol 7%; Preservative: Methylparaben, Propylparaben and Sodium Benzoate; Inactives: Artificial Boysenberry Flavor, Ascorbic Acid, Citric Acid, D&C Red No. The brand names mentioned on this website are the trademarks of their respective owners. 6, Propylene Glycol, Purified Water, Saccharin Sodium, Sodium Citrate and Sucrose Syrup. DISCLAIMER All labeling reflected on this website is for informational and promotional purposes only. It is not intended to be used by healthcare professionals or patients for the purpose of prescribing or administering these products. Questions regarding the current content of product labeling should be directed to Akorn's Customer Service department at 800.932.5676.

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