Hydroxychloroquine dose per kg

Discussion in 'Northwest Pharmaceuticals Canada' started by Viking!, 28-Feb-2020.

  1. skvayr XenForo Moderator

    Hydroxychloroquine dose per kg


    Most importantly, you help support continued development of this site. The majority of cases of retinotoxicity have occurred in patients that have had a cumulative dose exceeding 1000g of hydroxychloriquine (Plaquenil). This level is reached in about 7 years with the most common daily dose of Plaquenil, 400 mg/day (200 bid).

    Benefits drawbacks hydroxychloroquine Chloroquine tablets to buy Plaquenil mechanism of action

    Severe and irreversible retinal damage has been reported with the use of hydroxychloroquine. Risk factors for retinal damage include daily doses more than 6.5 mg/kg 5 mg/kg base of actual body weight, durations of use greater than 5 years, subnormal glomerular filtration, use of concomitant drugs such as tamoxifen, and concurrent macular disease. However, dose is usually not more than 800 mg for the first dose and not more than 400 mg for the next doses. Children—Dose is based on body weight and must be determined by your doctor. At first, 13 mg per kg of body weight taken as a single dose. Then, 6.5 mg per kg of body weight taken 6 hours, 24 hours, and 48 hours after the first dose. Kg or more 1 g chloroquine phosphate 600 mg base orally as an initial dose, followed by 500 mg chloroquine phosphate 300 mg base orally after 6 to 8 hours, then 500 mg chloroquine phosphate 300 mg base orally once a day on the next 2 consecutive days

    It now solely uses real body weight (rather than ideal body weight) based on new recommendations from a 2014 study (1). Disclaimer: This tool is designed to help eye care professionals better understand the risk the of retinotoxicity from hydroxychloroquine. Please note: This calculator was modified in 9/2015.

    Hydroxychloroquine dose per kg

    ACR Actual-weight hydroxychloroquine dosing works in SLE, up., What is Hydroxychloroquine? - GoodRx

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  5. The first dose of Plaquenil is usually taken one to two weeks before traveling to an area where malaria is prevalent. Doses are then continued for four weeks after exposure. per kilogram kg.

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    A risk factor for Plaquenil hydroxychloroquine retinotoxicity is a daily dose that exceeds 5.0 mg of drug per kg of body weight. The tool on the right simply calculates this threshold based on a patient’s real body weight. This apparently resulted in overdosing of thin patients. Thus, the patient’s real weight is now recommended as the basis for calculating the daily dose per weight in kg. Doses ≥ 5 mg/kg/day real weight of hydroxychloroquine 2.3 mg/kg/day of chloroquine are associated with higher risk of toxicity. The Hydroxychloroquine Dosing Calculator calculates appropriate daily dose of hydroxychloroquine. If a patient is on a dose that exceeds 5 mg/kg/day of real body.

     
  6. 4eRTeNoK Well-Known Member

    Plaquenil is the brand name for the prescription drug hydroxychloroquine. Must-Know Risks About Lupus SLE & Sinus Infections. HYDROXYCHLOROQUINE PLAQUENIL CARDIOTOXICITY AN UNCOMMON. Plaquenil hydroxychloroquine sulfate dose, indications.
     
  7. Lesnik1959 User

    This is not a list of all drugs or health problems that interact with hydroxychloroquine. Hydroxychloroquine Indications, Side Effects, Warnings. Hydroxychloroquine Oral Uses, Side Effects, Interactions. Hydroxychloroquine Drug Interactions - Significant - RxList
     
  8. Kesha V XenForo Moderator

    Aralen Chloroquine Uses, Dosage, Side Effects. Tablets containing 500 mg chloroquine phosphate USP, equivalent to 300 mg of chloroquine base, bottles of 25 NDC 0024-0084-01. White, film-coated convex, discoid tablet, ½ inch in diameter with an uncoated core, printed in black ink with a stylized “W” on one side and an “A77” on the other side.

    Hydroxychloroquine - Wikipedia