I don't get many side effects generally, but with prednisone I DO. It does help, but this can't be a long term affair. Plaquenil is a great drug (I have no experience with it, but many people with lupus take it). I'd ask your rheumy about it and have them explain why they made that choice for you. Prednisone is an intermediate acting corticosteroid-which means it has direct anti-inflamitory properties that take effect begining in a few hours. Is plaquenil another option instead of the prednisone? It is ment to get this undercontrol now and diminish your pain. Hydroxychloroquine for discoid lupus Hydroxychloroquine is associated with macular damage rash and diarrhea How many hours does plaquenil work Lupus nephritis is found among people who take Prednisone and Plaquenil, especially for people who are female, 20-29 old, have been taking the drugs for 5 - 10 years, also take medication Cellcept, and have Pain. This review analyzes which people have Lupus nephritis with Prednisone and Plaquenil. Plaquenil - Better Than Prednisone? I was first diagnosed with SLE in Sep 1991, after several weeks of stay in the hospital and countless rounds of blood tests. The conclusion is that I have an autoimmune disease that has affected my kidneys. Yes, if the plaquenil controls your Lupus flares, it is best to not use the prednisone. I hope you can get off of it completely, or at least take a small maintenance dose. Take it very slow. It has not direct anti-inflamitory properties and instead works on the immune system-though the mechanism is not known. Plaq is a longer time medication it may take two months before their is a noticable difference. Lupus plaquenil prednisone Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus, Immune & Autoimmune - Lupus Plaquenil - Better Than. Plaquenil actionWhat does hydroxychloroquine combined with methotrexate do for ra A few years ago I was diagnosed with lupus. I currently take mtx, 1 mg of folic acid a day, hydroxychloroquine plaquenil and a low dose of prednisone, 5mg. Mtx is used to treat certain types of cancers but at much higher and frequent doses than to treat RA and lupus,where mtx is taken once a week and the average dose is about 15mg. Prednisone sparing drugs" - Lupus - Inspire. Prednisone and Plaquenil question" Lupus Community.. Compare Plaquenil vs Prednisone - Comprehensive Analysis by Treato. Oral steroids – such as prednisone and prednisolone-- can be a lifesaving treatment for people with lupus. During serious lupus flares that affect organs such as the kidneys, high doses of. Dosing of prednisone varies widely depending on the state of the disease being treated. Doses used in rheumatoid arthritis are commonly 5-10mg daily, while doses needed in lupus and vasculitis are often 80mg daily, or sometimes higher. Prednisone usually achieves its effect within one – two hours. Lupus Support Group Lupus is an auto-immune disease in which the immune system cannot distinguish between threats like viruses and bacteria, and healthy cells and tissue. As a result, the body produces antibodies that inflict cell damage, most commonly targeting joints, skin, kidneys and the nervous system.