One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Keflex and plaquenil Hydroxychloroquine nclex Aug 29, 2014 Retinal toxicity of Plaquenil may manifest itself with subtle disturbances of the retinal pigment epithelium which may eventually lead to complete destruction of the macula in the form of bull’s-eye maculopathy. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. While today it is used to treat autoimmune conditions, such as rheumatoid arthritis and lupus, it was originally used as an anti-malaria drug. A rare side effect of Plaquenil involves visual changes or possible loss of vision —the side effect that is most worrisome for patients. The aforementioned rare side effect that affects vision hydroxychloroquine retinopathy, if caught early, may improve after discontinuation of Plaquenil. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Vision loss from plaquenil Plaquenil How I’m okay with it all — The Eye Doctor - Dr. Amy Falk OD., Plaquenil Side Effects on Your Eyes and Vision Canadian pharmacy hydroxychloroquineWhat exactly does plaquenil doRetinal damage from plaquenil Jun 13, 2019 people taking Plaquenil for 5 or more years; people taking Plaquenil at higher doses than recommended; people who already have retinal disease; people who already have kidney or liver disease; people over 60 years old; people who lose a lot of weight while taking Plaquenil. Tell your doctor if this happens as your dose may need to be lowered. Who Is at Risk for Vision Loss with Plaquenil? - American.. Taking Plaquenil for Rheumatoid Arthritis. Plaquenil How I’m okay with it all — The Eye Doctor - Dr.. Discussion. A risk factor for Plaquenil hydroxychloroquine retinotoxicity is a daily dose that exceeds 5.0 mg of drug per kg of body weight. The tool on the right simply calculates this threshold based on a patient’s real body weight. It’s important to understand that the daily dose is only one risk factor for plaquenil retinotoxicity. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Plaquenil hydroxychloroquine is a medicine commonly used to treat patients with systemic lupus erythematosus and rheumatoid arthritis. After prolonged use, it can sometimes damage the macula and cause central vision loss. Typically, the macula loses its orange pigment, giving the appearance of a bullseye.