It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Chloroquine malaria drug Plaquenil and depression Hydroxychloroquine is used in the treatment of various rheumatic conditions including systemic lupus erythematous. Hydroxychloroquine induced myopathy is rare adverse reaction but symptoms are usually recover after discontinuation of the drug. Here we report a case of woman with systemic lupus erythematosus who presented with myopathy after eight months treatment with hydroxychloroquine. Aug 29, 2014 Plaquenil or hydroxychloroquine HCQ is an anti-malarial medication that has been proven to be useful in the treatment of patients with rheumatoid The Risk of Retinal Toxicity with Plaquenil YOUR CREDIBLE SJÖGREN'S RESOURCE Chloroquine and hydroxychloroquine belong to the quinolone family. They are related drugs with similar clinical indications for use and similar manifestations of retinal toxicity, although their therapeutic and toxic doses differ. For prolonged treatment of lupus or arthritis, adverse effects include the acute symptoms, plus altered eye pigmentation, acne, anaemia, bleaching of hair, blisters in mouth and eyes, blood disorders, convulsions, vision difficulties, diminished reflexes, emotional changes, excessive coloring of the skin, hearing loss, hives, itching, liver problems or liver failure, loss of hair, muscle paralysis, weakness or atrophy, nightmares, psoriasis, reading difficulties, tinnitus, skin inflammation and scaling, skin rash, vertigo, weight loss, and occasionally urinary incontinence. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. For short-term treatment of acute malaria, adverse effects can include abdominal cramps, diarrhea, heart problems, reduced appetite, headache, nausea and vomiting. Hydroxychloroquine muscle toxicity Chloroquine‐induced cardiomyopathy a reversible cause of., The Risk of Retinal Toxicity with Plaquenil Rheumatoid arthritis hydroxychloroquine medicationsG6pd and hydroxychloroquine Many drugs used for therapeutic interventions can cause unanticipated toxicity in muscle tissue, often leading to considerable morbidity. A drug-induced, or toxic, myopathy is defined as the acute or subacute manifestation of myopathic symptoms such as muscle weakness, myalgia, creatine kinase elevation, or myoglobinuria that can occur in patients without muscle disease when they are exposed. Drug-related Myopathies of Which the Clinician Should Be Aware. Chloroquine and Hydroxychloroquine Toxicity Practice.. Confirmed Plaquenil Muscle Toxicity - Scleroderma - Inspire. Hydroxychloroquine belongs to a group of medicines known as antimalarials. It works by preventing or treating malaria, a red blood cell infection transmitted by the bite of a mosquito. However, this medicine is not used to treat severe or complicated malaria. Hydroxychloroquine is used to treat malaria. It is also used to prevent malaria infection in areas or regions where it is known that other medicines eg, chloroquine may not work. Hydroxychloroquine belongs to a group of medicines known as antimalarials. It works by preventing or treating malaria, a red blood cell infection transmitted by the. Background The American Academy of Ophthalmology recommendations on screening for chloroquine CQ and hydroxychloroquine HCQ retinopathy are revised in light of new information about the prevalence of toxicity, risk factors, fundus distribution, and effectiveness of screening tools.