Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Hydroxychloroquine and herb combination Chloroquine sleep Plaquenil and detached retina Hydroxychloroquine is a disease-modifying anti-rheumatic drug DMARD approved for adults with RA. It is often given in combination with methotrexate and sulfasalazine a treatment known as triple therapy, to help slow RA disease progression for patients who do not get relief from methotrexate therapy alone. The presence of retinal or visual field changes attributable to any 4-aminoquinoline compound like chloroquine, and in patients with known hypersensitivity to 4-aminoquinoline compounds. Hydroxychloroquine is an aminoquinoline like chloroquine. It is a commonly prescribed medication in the treatment of uncomplicated malaria, rheumatoid arthritis, chronic discoid lupus erythematosus, and systemic lupus erythematosus. Hydroxychloroquine is also used for the prophylaxis of malaria in regions where chloroquine resistance is unlikely. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Hydroxychloroquine in rheumatoid arthritis mechanism of action Hydroxychloroquine Plaquenil Success, Reviews and Side., Hydroxychloroquine TUSOM Pharmwiki Can plaquenil affect your thyroid Dec 24, 2010 A review of hydroxychloroquine as used by rheumatologists and its side effects. For more information, please visit. Rheumatoid Arthritis of the hand - Everything. Hydroxychloroquine for Rheumatoid Arthritis - YouTube. Hydroxychloroquine - DrugBank. PLAQUENIL HYDROXYCHLOROQUINE SULFATE TABLETS, USP DESCRIPTION. Mechanism of action. Hydroxychloroquine increases lysosomal pH in antigen-presenting cells. In inflammatory conditions, it blocks toll-like receptors on plasmacytoid dendritic cells PDCs. citation needed Hydroxychloroquine, by decreasing TLR signaling, reduces the activation of dendritic cells and the inflammatory process. Although the exact hydroxychloroquine mechanism of action is unknown when used to treat rheumatic diseases like rheumatoid arthritis, hydroxychloroquine inhibits communication between immune system cells. Hydroxychloroquine comes in a 200 mg tablet that are taken by mouth. 1, 2, 3, 5 Hydroxychloroquine is an antimalarial drug which is relatively safe and well-tolerated agent for the treatment of rheumatoid arthritis. Chloroquine is another antimalarial agent that is also sometimes used.