Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Sulfasalazine methotrexate plaquenil rheumatoid arthritis Drug treatment of chloroquine resistant malaria Chloroquine resazurin assay results Plaquenil cause disufl Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth. Women with rheumatic diseases, including inflammatory arthritis and systemic lupus erythematosus SLE, fare better in pregnancy when their disease is under good control1,2. The role of hydroxychloroquine HCQ for achieving this control is now recognized. Several studies demonstrate that patients with SLE who continue HCQ during pregnancy have decreased flares and improved pregnancy outcomes. Plaquenil hydroxychloroquine has been shown to improve physical function in up to 80% of patients with rheumatoid arthritis. Plaquenil hydroxychloroquine is commonly used for lupus in children because of less side effects compared to other medications. Plaquenil hydroxychloroquine helps minimize joint damage. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Hydroxychloroquine fda pregnancy category Safety of Immunosuppressive Drugs. - PubMed Central PMC, Too Little of a Good Thing Hydroxychloroquine in Pregnancy. Chloroquine over the counter The U. S. Food and Drug Administration FDA uses a pregnancy category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category C is given to medicines that have not been studied in pregnant humans but do appear to cause harm to the fetus in animal studies. Plaquenil and Pregnancy - Antibiotics Home Page. Plaquenil hydroxychloroquine Basics, Side Effects & Reviews.. DailyMed - HYDROXYCHLOROQUINE SULFATE tablet. Safe use of the drug in the treatment of juvenile arthritis has not been established. Precautions Dermatologic reactions to PLAQUENIL may occur and, therefore, proper care should be exercised when it is administered to any patient receiving a drug with a significant tendency to produce dermatitis. May 13, 2009 Background. The anti-malarial drugs Hydroxychloroquine HCQ is widely used to treat various rheumatic diseases mechanism of action of this drug is to increase the pH in acidic vesicles, inhibiting receptor mediated endocytosis that affects many cellular functions including antigen presentation, toll receptor signaling and post-transcriptional modification of proteins 2-4. Mar 29, 2019 The pregnancy exposure registries on this page are posted based on a sponsor or investigator's request to list their registry. FDA does not endorse any registry and is not responsible for the.