Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Plaquenil and ocular toxicity Hydroxychloroquine 400 mg side effects Fluorescein angiography and hydroxychloroquine maculopathy screening What are the side effects of hydroxychloroquine Plaquenil? Side effects include irritability, headache, weakness, hair lightening or loss, stomach upset, nausea, dizziness, muscle pain, rash and itching. Hydroxychloroquine typically is very well tolerated. Serious side effects are rare. The most common side effects are nausea and diarrhea, which often improve with time. Less common side effects include rash, changes in skin pigment such as darkening or dark spots, hair changes, and muscle weakness. Three anti-malarial drugs are prescribed for lupus symptoms. Hydroxychloroquine Plaquenil is the most commonly prescribed because it is generally believed to cause fewer side effects; chloroquine Aralen has a reputation for more serious side effects. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Plaquenil for lupus side effects Hydroxychloroquine Reviews Everyday Health, Hydroxychloroquine Plaquenil Chloroquine in typhoidPlaquenil toxicity treatmentDiazepam with plaquenilChloroquine-proguanil malaria prophylaxis Plaquenil. Uses. Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. It does not work against certain types of. Side Effects. Precautions. Interactions. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus.. Plaquenil side effects" Lupus Community - Support Group. Feb 19, 2020 Common side effects may include headache, dizziness, ringing in your ears; nausea, vomiting, stomach pain; loss of appetite, weight loss; mood changes, feeling nervous or irritable; skin rash or itching; or. hair loss. Upsides. Plaquenil hydroxychloroquine has been shown to improve physical function in up to 80% of patients with rheumatoid arthritis. Plaquenil hydroxychloroquine is commonly used for lupus in children because of less side effects compared to other medications. If you notice these less serious side effects, talk with your doctor Dry skin. Loss of appetite. Upset stomach or cramps. Diarrhea. Bleaching of hair or hair loss. Blue-back discoloration of skin, fingernails, or inside of the mouth.