Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Chloroquine phosphate and leather corals Plaquenil and bc Chloroquine hydrochloride injection Positive ANA at 80 and now negative. Support Forums. It all makes sense, but it seemed so extreme. To have a positive ANA for so long that suddenly became negative seemed strange to me. Yes, I have been taking Plaquenil since I was diagnosed--so going on four years now. My symptoms are more controlled now as compared to where I was at. An antinuclear antibody test looks for autoimmune diseases such as lupus or rheumatoid arthritis. The ANA blood test is just one part of a doctor’s autoimmune disease diagnosis, along with a. Positive ANA Turned Negative. April 26, 2007 By Arthritis Center. Question. For several years I have had recurrent unexplainable illnesses, rashes and arthritis-like symptoms. Finally during my last episode, I requested an ANA test, which returned positive. My doctor and I both felt like we were finally getting to the bottom of things and he. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Taking plaquenil with negative ana Positive ANA Negative anti-dsdna at titer? Lupus., Antinuclear Antibodies ANA Test - WebMD Hydroxychloroquine 200 mg acetaminophen 400 mgHydroxychloroquine lysosome blockerPlaquenil and weight Q5. My mother just passed away with Lupus and my uncle and my cousin also have lupus. I just had my first ANA that was speckled. My other previous ones had all been negative. I already have the ankles that swell constantly, the joint pain, the low blood counts, low D, low B12, and I’m throwing protein into the urine. Lupus and Testing Questions Answered. Positive ANA Turned Negative - Arthritis Information. Treating Lupus with Anti-Malarial Drugs Johns Hopkins.. Damage to the retina, the light sensitive portion of the inner eye, can occur with long-term use of Plaquenil or chloroquine Aralen. With Plaquenil, however, the most commonly prescribed anti-malarial, this sort of damage occurs only in 1 out of 5,000 people who take the drug for five years or more. If you go to the Mayo Clinic Lupus website it will give the info on there. It can also take years for an ANA to turn positive or sometimes when you blood is drawn it is negative at that time, but it does not mean it is always negative. It took me year and years of being ill to have a positive ANA and other blood work. Oct 29, 2009 At least it's something I'm going to continue to pursue. Maybe my ANA went negative because of the Plaquenil.with the other changes, I'm inclined to believe it had quite a lot, if not everything to do with the dietary changes. There was one negative to all the improved bloodwork, and that is that my CRP actually increased doubled, really.